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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. GMPS, guanine monphosphate synthetase
Sequence ID:NM_003875
RefSeqGene ID:NG_023247
Entrez Gene ID:8833
Ensembl ID:ENSG00000163655

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
LEUKEMIA, ACUTE MYELOGENOUSARHGEF12
CBFB
CEBPA
CHIC2
ETV6
FLT3
GATA2
JAK2
KIT
LPP
MLF1
MLLT10
NPM1
NSD1
NUP214
PICALM
RUNX1
RUNX1
SH3GL1
TERT
WHSC1L1

Cytogenetic Location (from UniGene)

Cytogenetic Location:3q24Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 118352702 - 118355029

 Exon Info From UCSC:
NM_003875

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4653684Full LengthBC012178guanine monphosphate synthetase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003866  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_003875 NP_003866 P49915 EC 6.3.5.2 GATase
GMP_synt_C
ExsB

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U10860 AAA60331 P49915 EC 6.3.5.2
BC012178 AAH12178 P49915 EC 6.3.5.2
DQ896621 ABM87620    
EU176462 ABW03913    
AK223399 BAD97119 Q53F90  
AK291504 BAF84193 A8K639  
AK315832 BAF98723 A8K639  
AK300787 BAG62449 B4DUT7  
AK302148 BAG63519 B4DXV7  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GMPS NP_003866 M.musculus Gmps 229363 Gene Info NP_001028472 98
R.norvegicus Gmps 295088   NP_001019925 98
A.gambiae AgaP_AGAP010139 1279559   XP_319294 62
D.melanogaster bur 45830   NP_620114 60
C.elegans M106.4 174672   NP_001076631 55

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)