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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. IDH3A, isocitrate dehydrogenase 3 (NAD+) alpha
Sequence ID:NM_005530
Entrez Gene ID:3419
Ensembl ID:ENSG00000166411

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:15q25.1-q25.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:15: 78449264 - 78462013

 Exon Info From UCSC:
NM_005530

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2989636Full LengthBC021967isocitrate dehydrogenase 3 (NAD+) alpha
5274718IncompleteBC036227isocitrate dehydrogenase 3 (NAD+) alpha

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005521  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_005530 NP_005521 P50213 EC 1.1.1.41 Iso_dh

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U07681 AAA85639 P50213 EC 1.1.1.41
BC021967 AAH21967 P50213 EC 1.1.1.41
DQ892774 ABM83700    
DQ893529 ABM84455    
DQ896022 ABM87021    
AK222973 BAD96693 Q53GF8  
AK296002 BAG58776 B4DJB4  
AK299970 BAG61796 B4DSY4  
AK315963 BAH14334 B7Z9J8  
AK316051 BAH14422 B7Z9J8  
AL442090 CAC09449 P50213 EC 1.1.1.41
CR749548 CAH18348 Q68D72  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens IDH3A NP_005521 M.musculus Idh3a 67834 Gene Info NP_083849 98
R.norvegicus Idh3a 114096   NP_446090 97
A.gambiae AgaP_AGAP002728 1273240   XP_312198 72
C.elegans F43G9.1 172655   NP_492330 71
D.melanogaster l(1)G0156 32940   NP_728257 71
N.crassa NCU07697 3878431   XP_962283 64
S.pombe idh2 2541260   NP_595203 62
A.thaliana IDH-VI 820139   NP_850549 57
A.thaliana IDH-V 831884   NP_568113 56
S.cerevisiae IDH2 854303   NP_014779 56

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)