Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SMC4, structural maintenance of chromosomes 4
Sequence ID:NM_001002799
NM_001002800
NM_005496
Entrez Gene ID:10051
Ensembl ID:ENSG00000113810

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:3q26.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 160117438 - 160151704

 Exon Info From UCSC:
NM_001002800
NM_005496

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100015924Full LengthBC148796structural maintenance of chromosomes 4
3460137IncompleteBC001557structural maintenance of chromosomes 4
4252738IncompleteBC070161structural maintenance of chromosomes 4
4996934IncompleteBC106033structural maintenance of chromosomes 4
6145405IncompleteBC065259structural maintenance of chromosomes 4
100015108BC146370structural maintenance of chromosomes 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005487  NP_001002800  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001002800 NP_001002800 Q9NTJ3 SMC_N
SMC_hinge
NM_005496 NP_005487 Q9NTJ3 SMC_N
SMC_hinge

Related Sequences

 
mRNAGenPeptSwissProt
AF092564 AAC72361 Q9NTJ3
BC001557 AAH01557 Q58F29
BC065259 AAH65259 Q6P169
BC070161 AAH70161 Q6NSG3
BC106033 AAI06034 Q58F29
BC146370 AAI46371  
BC148796 AAI48797  
AB019987 BAA73535 Q9NTJ3
AK122939 BAG53807 B3KVJ5
AK128143 BAG54637 B3KXX5
AL136877 CAB66811 Q9NTJ3
AL833949 CAD38803 Q9NTJ3

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SMC4 NP_001002800 M.musculus Smc4 70099 Gene Info NP_598547 90
R.norvegicus Smc4 295107   NP_001032262 90
A.gambiae AgaP_AGAP007826 1278132   XP_317674 44
A.thaliana SMC3 834917   NP_001190492 44
D.melanogaster glu 35001   NP_723996 40
S.pombe cut3 2539817   NP_595392 39
S.cerevisiae SMC4 850775   NP_013187 39
N.crassa NCU09063 3874714   XP_958567 37
P.falciparum PFE0450w 812851   XP_001351649 36

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)