Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PDE8B, phosphodiesterase 8B
Sequence ID:NM_001029851
NM_001029852
NM_001029853
NM_001029854
NM_003719
RefSeqGene ID:NG_023364
Entrez Gene ID:8622
Ensembl ID:ENSG00000113231

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
PIGMENTED NODULAR ADRENOCORTICAL DISEASE, PRIMARY, 3 
STRIATAL DEGENERATION, AUTOSOMAL DOMINANT 

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 76506741 - 76722458

 Exon Info From UCSC:
NM_001029851
NM_001029852
NM_001029853
NM_001029854
NM_003719

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100062824Full LengthBC156987phosphodiesterase 8B
4796558IncompleteBC047627phosphodiesterase 8B
5264475IncompleteBC035144phosphodiesterase 8B
100061565BC156215phosphodiesterase 8B

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003710  NP_001025025  NP_001025022  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001029851 NP_001025022     Response_reg
PDEase_I
PDE8
NM_001029852 NP_001025023      
NM_001029853 NP_001025024      
NM_001029854 NP_001025025     Response_reg
PDEase_I
PDE8
NM_003719 NP_003710 O95263 EC 3.1.4.17 Response_reg
PDEase_I
PAS
PDE8

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF079529 AAC69564 O95263 EC 3.1.4.17
BC035144 AAH35144 Q3ZCW6  
BC047627 AAH47627 Q3ZCR2  
BC156215 AAI56216    
BC156987 AAI56988    
AY129948 AAN71723 O95263 EC 3.1.4.17
AY129949 AAN71724 O95263 EC 3.1.4.17
AY423729 AAS00492 O95263 EC 3.1.4.17
AB085824 BAC53762 O95263 EC 3.1.4.17
AB085825 BAC53763 O95263 EC 3.1.4.17
AB085826 BAC53764 O95263 EC 3.1.4.17
AB085827 BAC53765 O95263 EC 3.1.4.17
AK002074 BAG51011 B3KMJ9  
AK023913 BAG51239 B3KN77  
AL831924 CAD38584 O95263 EC 3.1.4.17

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PDE8B NP_003710 R.norvegicus Pde8b 309962   NP_954889 98
M.musculus Pde8b 218461 Gene Info NP_758467 97
A.gambiae AgaP_AGAP007163 1269950   XP_308604 42
D.melanogaster Pde8 37741   NP_726352 41

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)