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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. LRP6, low density lipoprotein receptor-related protein 6
Sequence ID:NM_002336
RefSeqGene ID:NG_016168
Entrez Gene ID:4040
Ensembl ID:ENSG00000070018

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CORONARY ARTERY DISEASE, AUTOSOMAL DOMINANT, 2 

Cytogenetic Location (from UniGene)

Cytogenetic Location:12p13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 12268962 - 12397238

 Exon Info From UCSC:
NM_002336

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8992121Full LengthBC126405low density lipoprotein receptor-related protein 6
9052239Full LengthBC143725low density lipoprotein receptor-related protein 6
40125687Full LengthBC117136low density lipoprotein receptor-related protein 6

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002327  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_002336 NP_002327 O75581 EGF
Ldl_recept_a
Ldl_recept_b

Related Sequences

 
mRNAGenPeptSwissProt
AF074264 AAC33006 O75581
BC117136 AAI17137 O75581
BC126405 AAI26406 O75581
BC143725 AAI43726 B7ZLD0
AB209683 BAD92920 Q59EX8
AK074543 BAG51971 B3KQA9
AK074902 BAG52027 B3KQG5

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens LRP6 NP_002327 M.musculus Lrp6 16974 Gene Info NP_032540 98
R.norvegicus Lrp6 312781   NP_001101362 98

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)