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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. GTF2H1, general transcription factor IIH, polypeptide 1, 62kDa
Sequence ID:NM_001142307
NM_005316
Entrez Gene ID:2965
Ensembl ID:ENSG00000110768

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:11p15.1-p14Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 18343841 - 18387806

 Exon Info From UCSC:
NM_001142307
NM_005316

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2819217Full LengthBC000365general transcription factor IIH, polypeptide 1, 62kDa
2819217Full LengthBC004452general transcription factor IIH, polypeptide 1, 62kDa

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005307  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001142307 NP_001135779    
NM_005316 NP_005307 P32780 BSD
TFIIH_BTF_p62_N

Related Sequences

 
mRNAGenPeptSwissProt
M95809 AAA58399 P32780
BC000365 AAH00365 P32780
BC004452 AAH04452 P32780
DQ891408 ABM82334  
DQ894584 ABM85510  
AK027003 BAB15621 P32780
AK312974 BAG35811 B2R7G4
AK127204 BAG54452 B3KXE0
AK299621 BAG61549 B4DS87
AK299730 BAG61628 B4DSG6
CR457368 CAG33649 P32780

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GTF2H1 NP_001135779 M.musculus Gtf2h1 14884 Gene Info NP_032212 97
R.norvegicus Gtf2h1 361580   NP_001101955 97
D.melanogaster Tfb1 36598   NP_610957 50
A.gambiae AgaP_AGAP011110 1270814   XP_309535 47
C.elegans R02D3.3 176838   NP_499880 33
A.thaliana AT3G61420 825315   NP_191701 29
A.thaliana AT1G55750 842024   NP_175971 27

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)