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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CHRNA2, cholinergic receptor, nicotinic, alpha 2 (neuronal)
Sequence ID:NM_000742
RefSeqGene ID:NG_015827
Entrez Gene ID:1135
Ensembl ID:ENSG00000120903

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
EPILEPSY, NOCTURNAL FRONTAL LOBE, TYPE 4 

Cytogenetic Location (from UniGene)

Cytogenetic Location:8p21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 27319119 - 27336368

NM_000742 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1820102731727827319270
201130252732049527321509
302631352732474527324854
313631802732685127326895
318134012732727727327497
340236102732850227328710
361140832733634027336812

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40121686Full LengthBC153866cholinergic receptor, nicotinic, alpha 2 (neuronal)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000733  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000742 NP_000733 Q15822 Neur_chan_LBD
Neur_chan_memb

Related Sequences

 
mRNAGenPeptSwissProt
U62431 AAB40109 Q15822
BC153866 AAI53867 Q15822
AK296348 BAG59031 B4DK19
Y16281 CAA76154 Q15822

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CHRNA2 NP_000733 R.norvegicus Chrna2 170945   NP_596911 86
M.musculus Chrna2 110902 Gene Info NP_659052 86
A.gambiae AgaP_AGAP002972 1272988   XP_311921 50
D.melanogaster nAcRalpha-96Ab 42919   NP_524482 50

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)