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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. AKR7A2, aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
Sequence ID:NM_003689
Entrez Gene ID:8574
Ensembl ID:ENSG00000053371

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pineal gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p36.13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 19630458 - 19638608

NM_003689 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3625337Full LengthBC013996aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
3832140Full LengthBC004111aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
3898226Full LengthBC010852aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
4620484Full LengthBC011586aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
4642811Full LengthBC012171aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
3615805IncompleteBC007352aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003680  

Protein Infomation

NM_003689 NP_003680 O43488 EC 1.1.1.n11 Aldo_ket_red

Related Sequences

AF026947 AAC52104 O43488 EC 1.1.1.n11
BC004111 AAH04111 O43488 EC 1.1.1.n11
BC007352 AAH07352 O43488 EC 1.1.1.n11
BC010852 AAH10852 O43488 EC 1.1.1.n11
BC011586 AAH11586 O43488 EC 1.1.1.n11
BC012171 AAH12171 O43488 EC 1.1.1.n11
BC013996 AAH13996 O43488 EC 1.1.1.n11
BT007347 AAP36011 O43488 EC 1.1.1.n11
DQ891003 ABM81929    
DQ894182 ABM85108    
AK303131 BAG64236 B4DZX4  
Y16675 CAA76347 O43488 EC 1.1.1.n11
BK000395 DAA00088 O43488 EC 1.1.1.n11

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens AKR7A2 NP_003680 R.norvegicus Akr7a2 171445   NP_599234 88
M.musculus Akr7a5 110198 Gene Info NP_079613 88

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta