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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PRKRA, protein kinase, interferon-inducible double stranded RNA dependent activator
Sequence ID:NM_001139517
RefSeqGene ID:NG_009053
Entrez Gene ID:8575
Ensembl ID:ENSG00000180228

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q31.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 179296140 - 179315853

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3503747Full LengthBC009470protein kinase, interferon-inducible double stranded RNA dependent activator

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003681  

Protein Infomation

NM_001139517 NP_001132989    
NM_001139518 NP_001132990    
NM_003690 NP_003681 O75569 dsrm

Related Sequences

AF072860 AAC25672 O75569
AF083033 AAD33099 O75569
BC009470 AAH09470 O75569
AY251164 AAP20061 O75569
BT007243 AAP35907 O75569
EU831719 ACE86553  
EU831635 ACE87235  
AK223107 BAD96827 O75569
AK290601 BAF83290 O75569
AK296019 BAG58789 B4DJC7
AL136615 CAB66550 O75569
AL833867 CAD38725 O75569
CR533525 CAG38556 O75569

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PRKRA NP_003681 M.musculus Prkra 23992 Gene Info NP_036001 98
R.norvegicus Prkra 311130   NP_001019951 98

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)