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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. SIX3, SIX homeobox 3
Sequence ID:NM_005413
RefSeqGene ID:NG_016222
Entrez Gene ID:6496
Ensembl ID:ENSG00000138083

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:2p21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 45169036 - 45172390

NM_005413 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100016368Full LengthBC153026SIX homeobox 3
5405743IncompleteBC030289SIX homeobox 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005404  

Protein Infomation

NM_005413 NP_005404 O95343 Homeobox

Related Sequences

BC030289 AAH30289 A0PJI2
BC153026 AAI53027  
AJ012611 CAB42539 O95343
AL162671 CAB83141 Q9NSJ2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SIX3 NP_005404 M.musculus Six3 20473 Gene Info NP_035511 98
R.norvegicus Six3 78974   NP_076480 98

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)