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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PEX5, peroxisomal biogenesis factor 5
Sequence ID:NM_000319
NM_001131023
NM_001131024
NM_001131025
NM_001131026
RefSeqGene ID:NG_008448
Entrez Gene ID:5830
Ensembl ID:ENSG00000139197

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, salivary gland, skin, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
PEROXISOME BIOGENESIS DISORDER 1A (ZELLWEGER)PEX1
PEX10
PEX12
PEX13
PEX14
PEX19
PEX2
PEX26
PEX26
PEX3
PEX3
PEX6
PEROXISOME BIOGENESIS DISORDER 2A (ZELLWEGER) 
PEROXISOME BIOGENESIS DISORDER 2BPEX1
PEX10
PEX13
PEX26
PEX26

Cytogenetic Location (from UniGene)

Cytogenetic Location:12p13.31Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 7342326 - 7364079

 Exon Info From UCSC:
NM_000319
NM_001131023
NM_001131024
NM_001131025
NM_001131026

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3872822Full LengthBC010621peroxisomal biogenesis factor 5

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000310  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000319 NP_000310   TPR_1
NM_001131023 NP_001124495    
NM_001131024 NP_001124496    
NM_001131025 NP_001124497 P50542  
NM_001131026 NP_001124498    

Related Sequences

 
mRNAGenPeptSwissProt
U19721 AAC50103 P50542
BC010621 AAH10621 P50542
DQ891142 ABM82068  
DQ894321 ABM85247  
AK292256 BAF84945 P50542
AK299105 BAG61162 B4DR50
AK299534 BAG61481 B4DS19
AK301700 BAG63172 B4DWW0
AK302742 BAG63957 P50542
AK303515 BAG64544 B4E0T2
AK316250 BAH14621 P50542
X84899 CAA59324 P50542
Z48054 CAA88131 P50542

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PEX5 NP_001124498 R.norvegicus Pex5 312703   XP_232343 95
M.musculus Pex5 19305 Gene Info NP_033021 94
D.melanogaster CG14815 31141   NP_569949 44
A.gambiae AgaP_AGAP006820 1270245   XP_308925 42
N.crassa NCU02960 3881510   XP_965347 38
C.elegans prx-5 174392   NP_001022019 38
A.thaliana PEX5 835728   NP_200440 37
S.cerevisiae PEX5 851831   NP_010530 31

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)