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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. POLA1, polymerase (DNA directed), alpha 1, catalytic subunit
Sequence ID:NM_016937
RefSeqGene ID:NG_016798
Entrez Gene ID:5422
Ensembl ID:ENSG00000101868

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:Xp22.1-p21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:X: 24712057 - 24746746

 Exon Info From UCSC:
NM_016937

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9094447IncompleteBC172871polymerase (DNA directed), alpha

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_058633  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_016937 NP_058633 P09884 EC 2.7.7.7 DNA_pol_B
DNA_pol_B_exo

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
X06745 CAA29920 P09884 EC 2.7.7.7

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens POLA1 NP_058633 M.musculus Pola1 18968 Gene Info NP_032918 88
R.norvegicus Pola1 85241   XP_242396 88
A.gambiae AgaP_AGAP001929 1281195   XP_321134 45
D.melanogaster DNApol-alpha180 42553   NP_536736 43
A.thaliana ICU2 836845   NP_201511 40
C.elegans Y47D3A.29 176544   NP_499437 40
S.pombe pol1 2543629   NP_594186 38
S.cerevisiae POL1 855621   NP_014297 36
N.crassa NCU07870 3879279   XP_963131 36

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)