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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PDE6A, phosphodiesterase 6A, cGMP-specific, rod, alpha
Sequence ID:NM_000440
RefSeqGene ID:NG_009102
Entrez Gene ID:5145
Ensembl ID:ENSG00000132915

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
RETINITIS PIGMENTOSA 43 

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q31.2-q34Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 149237517 - 149324356

 Exon Info From UCSC:
NM_000440

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5492027Full LengthBC035909phosphodiesterase 6A, cGMP-specific, rod, alpha

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000431  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000440 NP_000431 P16499 EC 3.1.4.35 PDEase_I
GAF

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M26061 AAB69155 P16499 EC 3.1.4.35
BC035909 AAH35909 P16499 EC 3.1.4.35
AB593141 BAJ84077 F1T0K3  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PDE6A NP_000431 M.musculus Pde6a 225600 Gene Info NP_666198 95
R.norvegicus Pde6a 307401   NP_001100856 95

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta