Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. IL12RB1, interleukin 12 receptor, beta 1
Sequence ID:NM_005535
NM_153701
RefSeqGene ID:NG_007366
Entrez Gene ID:3594
Ensembl ID:ENSG00000096996

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
BCG INFECTION, GENERALIZED FAMILIALIFNGR1
IFNGR2
IL12B
STAT1
STAT1

Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 18181371 - 18197740

 Exon Info From UCSC:
NM_005535
NM_153701

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9021402Full LengthBC137404interleukin 12 receptor, beta 1
9021404Full LengthBC137406interleukin 12 receptor, beta 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005526  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_005535 NP_005526 P42701 fn3
NM_153701 NP_714912    

Related Sequences

 
mRNAGenPeptSwissProt
U03187 AAA21340 P42701
BC029121 AAH29121 P42701
BC137404 AAI37405 P42701
BC137406 AAI37407 P42701
EU832545 ACE86947  
EU832592 ACE86994  
EU832463 ACE87635  
EU832511 ACE87683  
JF432889 ADZ16106  
AK290423 BAF83112 P42701

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens IL12RB1 NP_005526 M.musculus Il12rb1 16161 Gene Info NP_032379 57
R.norvegicus Il12rb1 171333   XP_344494 54

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta