Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MARK2, MAP/microtubule affinity-regulating kinase 2
Sequence ID:NM_001039469
NM_001163296
NM_001163297
NM_004954
NM_017490
RefSeqGene ID:NG_029771
Entrez Gene ID:2011
Ensembl ID:ENSG00000072518

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q13.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 63606399 - 63677051

 Exon Info From UCSC:
NM_001039469
NM_001163296
NM_001163297
NM_004954
NM_017490

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4591688Full LengthBC084540MAP/microtubule affinity-regulating kinase 2
3139103IncompleteBC008771MAP/microtubule affinity-regulating kinase 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004945  NP_059672  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001039469 NP_001034558 Q7KZI7 EC 2.7.11.1
EC 2.7.11.26
 
NM_001163296 NP_001156768      
NM_001163297 NP_001156769      
NM_004954 NP_004945     Pkinase
UBA
KA1
Pkinase_Tyr
NM_017490 NP_059672     Pkinase
UBA
KA1
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC008771 AAH08771 Q7KZI7 EC 2.7.11.1
EC 2.7.11.26
BC084540 AAH84540 Q7KZI7 EC 2.7.11.1
EC 2.7.11.26
AF387638 AAK82368 Q7KZI7 EC 2.7.11.1
EC 2.7.11.26
BT007342 AAP36006 Q7KZI7 EC 2.7.11.1
EC 2.7.11.26
AY562187 AAT67601 Q5DNC6  
AY562188 AAT67602 Q5DNC5  
DQ890693 ABM81619    
DQ893876 ABM84802    
AB188493 BAD37141 Q7KZI7 EC 2.7.11.1
EC 2.7.11.26
AK290339 BAF83028 A8K2S4  
AB271694 BAF96440 A9CP04  
X97630 CAA66229 Q7KZI7 EC 2.7.11.1
EC 2.7.11.26
Z25427 CAA80914 Q7KZI7 EC 2.7.11.1
EC 2.7.11.26

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MARK2 NP_059672 M.musculus Mark2 13728 Gene Info NP_031954 98
R.norvegicus Mark2 60328   NP_067731 97
A.gambiae AgaP_AGAP012064 3291504   XP_552140 59

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)