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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. AKR1C4, aldo-keto reductase family 1, member C4
Sequence ID:NM_001818
RefSeqGene ID:NG_031872
Entrez Gene ID:1109
Ensembl ID:ENSG00000198610

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDDTPSNPSNP: GeneViewSNP: VarViewAssemblies

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:10p15.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 5238830 - 5260723

NM_001818 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
111752387975238913
11828552421435242310
28640252463395246455
40348052477195247796
48160352482375248359
60471352545785254687
71487952549565255121
88096252586735258755
963119252606805260909

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4734943Full LengthBC020744aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001809  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001818 NP_001809   Aldo_ket_red

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M33375 AAA35658 P17516 EC 1.1.1.50
EC 1.1.1.225
S68287 AAD14010 P17516 EC 1.1.1.50
EC 1.1.1.225
BC020744 AAH20744 P17516 EC 1.1.1.50
EC 1.1.1.225
DQ891424 ABM82350    
DQ894598 ABM85524    
D26125 BAA05122 P17516 EC 1.1.1.50
EC 1.1.1.225
AB031085 BAA92885 P17516 EC 1.1.1.50
EC 1.1.1.225
AB045829 BAA99542 P17516 EC 1.1.1.50
EC 1.1.1.225

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens AKR1C4 NP_001809 M.musculus Akr1c6 83702 Gene Info NP_085114 76
R.norvegicus Akr1c1 307092   NP_001028869 74
A.thaliana AT5G01670 831701   NP_195787 38

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)