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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. ACO1, aconitase 1, soluble
Sequence ID:NM_002197
Entrez Gene ID:48
Ensembl ID:ENSG00000122729

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:9p21.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:9: 32384645 - 32452784

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3915517Full LengthBC018103aconitase 1, soluble

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002188  

Protein Infomation

NM_002197 NP_002188 P21399 EC Aconitase

Related Sequences

M58510 AAA69900 P21399 EC
AF261088 AAF99681 Q9HBB2  
BC018103 AAH18103 P21399 EC
AB209480 BAD92717 Q59FI0  
Z11559 CAA77651 P21399 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens ACO1 NP_002188 R.norvegicus Aco1 50655   NP_059017 93
M.musculus Aco1 11428 Gene Info NP_031412 93
A.gambiae AgaP_AGAP007258 1269890   XP_308544 69
D.melanogaster Irp-1B 41269   NP_524303 69
D.melanogaster Irp-1A 42689   NP_477371 68
C.elegans aco-1 181324   NP_509898 64
A.thaliana ACO3 815120   NP_178634 62
A.thaliana ACO2 828805   NP_567763 61
A.thaliana ACO1 829737   NP_195308 61
P.falciparum PF13_0229 814196   XP_001350142 54

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)