Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. CRKL, v-crk sarcoma virus CT10 oncogene homolog (avian)-like
Sequence ID:NM_005207
RefSeqGene ID:NG_016354
Entrez Gene ID:1399
Ensembl ID:ENSG00000099942

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:22q11.21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:22: 21305018 - 21307890

NM_005207 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6046673Full LengthBC043500v-crk sarcoma virus CT10 oncogene homolog (avian)-like
4749267IncompleteBC033281v-crk sarcoma virus CT10 oncogene homolog (avian)-like
5273862IncompleteBC044621v-crk sarcoma virus CT10 oncogene homolog (avian)-like

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005198  

Protein Infomation

NM_005207 NP_005198 P46109 SH2

Related Sequences

BC043500 AAH43500 P46109
AK292909 BAF85598 P46109
X59656 CAA42199 P46109
CR456423 CAG30309 P46109
CU012984 CAK54415  
CU013272 CAK54714  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens CRKL NP_005198 M.musculus Crkl 12929 Gene Info NP_031790 97
R.norvegicus Crkl 287942   NP_001008285 97

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta