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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. FBXW7, F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
Sequence ID:NM_001013415
NM_001257069
NM_018315
NM_033632
RefSeqGene ID:NG_029466
Entrez Gene ID:55294
Ensembl ID:ENSG00000109670

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:4q31.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 153243964 - 153273874

 Exon Info From UCSC:
NM_001013415
NM_018315
NM_033632

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9052462Full LengthBC143944F-box and WD repeat domain containing 7
40125795Full LengthBC117244F-box and WD repeat domain containing 7
40125797Full LengthBC117246F-box and WD repeat domain containing 7
5260084IncompleteBC037320F-box and WD repeat domain containing 7

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_361014  NP_060785  NP_001013433  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001013415 NP_001013433   WD40
F-box
NM_001257069 NP_001243998    
NM_018315 NP_060785   WD40
F-box
NM_033632 NP_361014 Q969H0 WD40
F-box

Related Sequences

 
mRNAGenPeptSwissProt
AY008274 AAG16640 Q969H0
BC037320 AAH37320 Q969H0
BC117244 AAI17245 Q969H0
BC117246 AAI17247 Q969H0
BC143944 AAI43945 Q969H0
AY033553 AAK57547 Q969H0
AF383178 AAK60269 Q969H0
AF411971 AAL06290 Q969H0
AF411972 AAL06291 Q969H0
AY049984 AAL07271 Q969H0
HQ258348 ADR83102  
HQ873864 AEK48270 G0Z2K0
HQ873865 AEK48271 G0Z2K0
HQ873866 AEK48272 G0Z2K0
HQ873867 AEK48273 G0Z2K0
HQ873868 AEK48274 G0Z2K0
HQ873869 AEK48275 G0Z2K0
HQ873870 AEK48276 G0Z2K0
AK001933 BAA91986 Q969H0
AB209725 BAD92962 Q59ET6
AK223449 BAD97169 Q53F40
AK294568 BAH11814 B7Z2C8
AK299722 BAH13109 B7Z623
CR749305 CAH18160 Q969H0

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FBXW7 NP_361014 M.musculus Fbxw7 50754 Gene Info NP_001171245 96
R.norvegicus LOC100360914 100360914   XP_002729135 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta