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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CYB5R3, cytochrome b5 reductase 3
Sequence ID:NM_000398
NM_001129819
NM_001171660
NM_001171661
NM_007326
RefSeqGene ID:NG_012194
Entrez Gene ID:1727
Ensembl ID:ENSG00000100243

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
METHEMOGLOBINEMIA, TYPE I 

Cytogenetic Location (from UniGene)

Cytogenetic Location:22q13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:22: 43015692 - 43045341

 Exon Info From UCSC:
NM_000398
NM_001129819
NM_001171660
NM_001171661
NM_007326

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3450773Full LengthBC004821cytochrome b5 reductase 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_015565  NP_000389  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000398 NP_000389 P00387 EC 1.6.2.2 NAD_binding_1
FAD_binding_6
NM_001129819 NP_001123291      
NM_001171660 NP_001165131      
NM_001171661 NP_001165132      
NM_007326 NP_015565     NAD_binding_1
FAD_binding_6

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M16461 AAA52306 P00387 EC 1.6.2.2
M16462 AAA52307 P00387 EC 1.6.2.2
BC004821 AAH04821 P00387 EC 1.6.2.2
AF361370 AAL87744 P00387 EC 1.6.2.2
BT009821 AAP88823 P00387 EC 1.6.2.2
AY421733 AAR38507 Q6TGM5  
AY421734 AAR38508 Q6TGM4  
AK124528 BAC85875 Q6ZVI6  
AK302204 BAH13649 P00387 EC 1.6.2.2
AJ010116 CAA09006 P00387 EC 1.6.2.2
AJ010117 CAA09007 P00387 EC 1.6.2.2
AJ010118 CAA09008 P00387 EC 1.6.2.2
Y09501 CAA70696 P00387 EC 1.6.2.2
AJ310899 CAC84523 P00387 EC 1.6.2.2
AJ310900 CAC84524 P00387 EC 1.6.2.2
CR456435 CAG30321 P00387 EC 1.6.2.2
CU012995 CAK54426    
CU013283 CAK54725    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CYB5R3 NP_001165131 M.musculus Cyb5r3 109754 Gene Info NP_084063 87
R.norvegicus Cyb5r3 25035   NP_620232 87
A.thaliana NIA1 844112   NP_177899 51
A.thaliana NIA2 840630   NP_174901 46

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)