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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PRPS1, phosphoribosyl pyrophosphate synthetase 1
Sequence ID:NM_001204402
NM_002764
RefSeqGene ID:NG_008407
Entrez Gene ID:5631
Ensembl ID:ENSG00000147224

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
ARTS SYNDROME 
CHARCOT-MARIE-TOOTH DISEASE, X-LINKED RECESSIVE, 5 
GOUT, PRPS-RELATED 

Cytogenetic Location (from UniGene)

Cytogenetic Location:Xq21.32-q24Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:X: 106871836 - 106893960

Transcript StartTranscript EndChromosomal Start Chromosomal End
1327106871653106871979
328511106882524106882707
512610106884131106884229
611735106885595106885719
736909106888406106888579
9101069106890835106890994
10702155106893169106894254

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3542584Full LengthBC001605phosphoribosyl pyrophosphate synthetase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002755  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001204402 NP_001191331      
NM_002764 NP_002755 P60891 EC 2.7.6.1 Pribosyltran

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC001605 AAH01605 P60891 EC 2.7.6.1
DQ895833 ABM86759    
EU176362 ABW03813    
D00860 BAA00733 P60891 EC 2.7.6.1
AK223169 BAD96889 Q53FW2  
AK312706 BAG35584 B2R6T7  
AK297968 BAG60278 B4DNL6  
AK316467 BAH14838 B7ZB02  
X15331 CAA33386 P60891 EC 2.7.6.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PRPS1 NP_002755 M.musculus Prps1 19139 Gene Info NP_067438 100
R.norvegicus Prps1 29562   NP_058939 100
S.cerevisiae PRS3 856375   NP_011852 61

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)