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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. APAF1, apoptotic peptidase activating factor 1
Sequence ID:NM_001160
NM_013229
NM_181861
NM_181868
NM_181869
RefSeqGene ID:NG_029094
Entrez Gene ID:317
Ensembl ID:ENSG00000120868

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:12q23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 99042137 - 99129204

 Exon Info From UCSC:
NM_001160
NM_013229
NM_181861
NM_181868
NM_181869

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9007183Full LengthBC150255apoptotic peptidase activating factor 1
9020521Full LengthBC136531apoptotic peptidase activating factor 1
9020522Full LengthBC136532apoptotic peptidase activating factor 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_863651  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001160 NP_001151    
NM_013229 NP_037361    
NM_181861 NP_863651 O14727 WD40
CARD
NB-ARC
NM_181868 NP_863658    
NM_181869 NP_863659    

Related Sequences

 
mRNAGenPeptSwissProt
AF013263 AAC51678 O14727
AF149794 AAD34016 O14727
AF134397 AAD38344 O14727
BC136531 AAI36532 O14727
BC136532 AAI36533 O14727
BC150255 AAI50256 A7E2A2
AF248734 AAK28401 O14727
EF560718 ABQ59028 A5YM44
AB007873 BAA24843 O14727
AB103079 BAC77343 O14727
AJ243003 CAB55579 O14727
AJ243004 CAB55580 O14727
AJ243005 CAB55581 O14727
AJ243006 CAB55582 O14727
AJ243007 CAB55583 O14727
AJ243008 CAB55584 O14727
AJ243009 CAB55585 O14727
AJ243010 CAB55586 O14727
AJ243011 CAB55587 O14727
AJ243048 CAB55588 O14727
AJ243107 CAB56462 O14727

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens APAF1 NP_863651 R.norvegicus Apaf1 78963   NP_076469 87
M.musculus Apaf1 11783 Gene Info NP_001036023 87

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta