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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. SMPD2, sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
Sequence ID:NM_003080
Entrez Gene ID:6610
Ensembl ID:ENSG00000135587

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:6q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 109761965 - 109765122

NM_003080 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1444109761930109762373
445541109762559109762655
542618109762754109762830
619712109763176109763269
713802109763412109763501
803885109763745109763827
8861018109763954109764086
10191123109764179109764283
11241277109764469109764622
12781679109764719109765120

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3509845Full LengthBC000038sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003071  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_003080 NP_003071 O60906 EC 3.1.4.12 Exo_endo_phos

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC000038 AAH00038 O60906 EC 3.1.4.12
DQ891879 ABM82805    
HQ447883 ADQ32367    
AK313515 BAG36295 B2R8U8  
AJ222801 CAA10995 O60906 EC 3.1.4.12

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SMPD2 NP_003071 R.norvegicus Smpd2 83537   NP_112650 79
M.musculus Smpd2 20598 Gene Info NP_033239 77
C.elegans T27F6.6 173118   NP_493169 45

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta