Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SRD5A1, steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
Sequence ID:NM_001047
Entrez Gene ID:6715
Ensembl ID:ENSG00000145545

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:5p15Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 6633562 - 6669675

NM_001047 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
148366334996633981
48465066519546652120
65175266561906656291
75390366629286663078
904226266683146669672

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3683274Full LengthBC007033steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
3868483Full LengthBC008673steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001038  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001047 NP_001038 P18405 EC 1.3.1.30 Steroid_dh

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M32313 AAA35490 P18405 EC 1.3.1.30
AF052126 AAC28620 P18405 EC 1.3.1.30
AF113128 AAF14869 P18405 EC 1.3.1.30
BC007033 AAH07033 P18405 EC 1.3.1.30
BC008673 AAH08673 P18405 EC 1.3.1.30
BT006834 AAP35480 P18405 EC 1.3.1.30
DQ891537 ABM82463    
DQ894726 ABM85652    
AK313070 BAG35898 P18405 EC 1.3.1.30
AK297208 BAH12524 B7Z4D8  
AK297511 BAH12598 B7Z4L2  
AK315996 BAH14367 B7Z4L2  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SRD5A1 NP_001038 M.musculus Srd5a1 78925 Gene Info NP_780492 63
R.norvegicus Srd5a1 24950   NP_058766 62
A.thaliana DET2 818383   NP_181340 46
S.pombe SPAC9.08c 2543655   NP_593351 39
N.crassa NCU03337 3872611   XP_956446 33

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)