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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. LIAS, lipoic acid synthetase
Sequence ID:NM_006859
NM_194451
RefSeqGene ID:NG_032111
Entrez Gene ID:11019
Ensembl ID:ENSG00000121897

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:4p14Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 39471679 - 39479155

 Exon Info From UCSC:
NM_006859
NM_194451

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4841470Full LengthBC023635lipoic acid synthetase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_919433  NP_006850  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_006859 NP_006850 O43766 EC 2.8.1.8 Radical_SAM
NM_194451 NP_919433     Radical_SAM

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC023635 AAH23635 O43766 EC 2.8.1.8
BC062751 AAH62751 Q6P5Q6  
HQ447772 ADQ32257    
AK291985 BAF84674 Q6P5Q6  
AK292238 BAF84927 O43766 EC 2.8.1.8
AK303429 BAG64479 B4E0L7  
AJ224162 CAA11859 O43766 EC 2.8.1.8

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens LIAS NP_006850 R.norvegicus Lias 305348   NP_001012037 92
M.musculus Lias 79464 Gene Info NP_077791 91
D.melanogaster Las 40259   NP_524183 68
A.gambiae AgaP_AGAP010568 1275302   XP_314540 67
N.crassa NCU00565 3880875   XP_964726 66
A.thaliana AT5G08415 830740   NP_568196 62
S.pombe SPBC8D2.15 2541234   NP_595577 62
P.falciparum MAL13P1.220 813778   XP_001350160 62
C.elegans M01F1.3 3564813   NP_497722 59
S.cerevisiae LIP5 854371   NP_014839 59

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)