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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. LIAS, lipoic acid synthetase
Sequence ID:NM_006859
RefSeqGene ID:NG_032111
Entrez Gene ID:11019
Ensembl ID:ENSG00000121897

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:4p14Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 39471679 - 39479155

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4841470Full LengthBC023635lipoic acid synthetase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_919433  NP_006850  

Protein Infomation

NM_006859 NP_006850 O43766 EC Radical_SAM
NM_194451 NP_919433     Radical_SAM

Related Sequences

BC023635 AAH23635 O43766 EC
BC062751 AAH62751 Q6P5Q6  
HQ447772 ADQ32257    
AK291985 BAF84674 Q6P5Q6  
AK292238 BAF84927 O43766 EC
AK303429 BAG64479 B4E0L7  
AJ224162 CAA11859 O43766 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens LIAS NP_006850 R.norvegicus Lias 305348   NP_001012037 92
M.musculus Lias 79464 Gene Info NP_077791 91
D.melanogaster Las 40259   NP_524183 68
A.gambiae AgaP_AGAP010568 1275302   XP_314540 67
N.crassa NCU00565 3880875   XP_964726 66
A.thaliana AT5G08415 830740   NP_568196 62
S.pombe SPBC8D2.15 2541234   NP_595577 62
P.falciparum MAL13P1.220 813778   XP_001350160 62
C.elegans M01F1.3 3564813   NP_497722 59
S.cerevisiae LIP5 854371   NP_014839 59

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)