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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. LATS1, LATS, large tumor suppressor, homolog 1 (Drosophila)
Sequence ID:NM_001270519
NM_004690
NR_073033
Entrez Gene ID:9113
Ensembl ID:ENSG00000131023

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:6q25.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 149982503 - 150039392

Transcript StartTranscript EndChromosomal Start Chromosomal End
21325149982050149983373
13261432149997395149997501
14331615149997690149997872
16162198150001010150001592
21993712150004214150005727
37133860150016209150016356
38614348150022914150023401
43494756150038984150039391

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3632571Full LengthBC002767LATS, large tumor suppressor, homolog 1 (Drosophila)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004681  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001270519 NP_001257448      
NM_004690 NP_004681 O95835 EC 2.7.11.1 Pkinase
Pkinase_C
UBA

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF104413 AAD16882 O95835 EC 2.7.11.1
AF164041 AAD50272 O95835 EC 2.7.11.1
BC002767 AAH02767 O95835 EC 2.7.11.1
BC015665 AAH15665 Q6PJG3  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens LATS1 NP_004681 R.norvegicus Lats1 308265   NP_001128015 98
M.musculus Lats1 16798 Gene Info NP_034820 93
A.gambiae AgaP_AGAP003618 1274280   XP_313377 54
D.melanogaster wts 43651   NP_733403 52

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)