Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. ABCC8, ATP-binding cassette, sub-family C (CFTR/MRP), member 8
Sequence ID:NM_000352
RefSeqGene ID:NG_008867
Entrez Gene ID:6833
Ensembl ID:ENSG00000006071

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
DIABETES MELLITUS, NON-INSULIN-DEPENDENTAKT2
CDKAL1
ENPP1
GCGR
GCK
GPD2
HMGA1
HMGA1
HNF1A
HNF1B
HNF4A
IGF2BP2
IL6
IRS1
IRS2
KCNJ11
LIPC
MAPK8IP1
MTNR1B
NEUROD1
NEUROD1
NEUROD1
PAX4
PDX1
PPARG
PTPN1
RETN
SLC2A4
SLC30A8
TCF7L2
VEGFA
WFS1
WFS1
DIABETES MELLITUS, PERMANENT NEONATALGCK
INS
KCNJ11
DIABETES MELLITUS, TRANSIENT NEONATAL 2 
HYPERINSULINEMIC HYPOGLYCEMIA, FAMILIAL, 1 
HYPOGLYCEMIA OF INFANCY, LEUCINE-SENSITIVE 

Cytogenetic Location (from UniGene)

Cytogenetic Location:11p15.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 17417465 - 17498366

 Exon Info From UCSC:
NM_000352

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100068219Full LengthBC167829ATP-binding cassette, sub-family C (CFTR/MRP), member 8

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000343  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000352 NP_000343 Q09428 ABC_tran
ABC_membrane
Miro

Related Sequences

 
mRNAGenPeptSwissProt
L40625 AAA99227 Q09428
L78207 AAB02278 Q09428
U63421 AAB36699 Q09428
AF087138 AAC36724 Q09428
BC167829 AAI67829 Q09428
HM635782 ADM67556 Q09428
AB209084 BAD92321 Q59GM5
AK297560 BAH12616 B7Z4N0

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ABCC8 NP_000343 M.musculus Abcc8 20927 Gene Info NP_035640 96
R.norvegicus Abcc8 25559   NP_037171 96
A.gambiae AgaP_AGAP009799 3292067   XP_553659 41
D.melanogaster Sur 34350   NP_477472 35

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)