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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. TIRAP, toll-interleukin 1 receptor (TIR) domain containing adaptor protein
Sequence ID:NM_001039661
NM_148910
NM_052887
RefSeqGene ID:NG_011523
Entrez Gene ID:114609
Ensembl ID:ENSG00000150455

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
MALARIA, CEREBRALCD36
CISH
CR1
DARC
FCGR2B
GYPA
GYPC
ICAM1
NOS2
SLC4A1
TNF
MYCOBACTERIUM TUBERCULOSISCCL2
CD209
CISH
CTSZ
IFNG
IFNGR1
IRGM
IRGM
MC3R
SLC11A1
SP110

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q24.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 126160789 - 126163582

 Exon Info From UCSC:
NM_001039661
NM_148910

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5216171Full LengthBC032474toll-interleukin 1 receptor (TIR) domain containing adaptor protein

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001039661 NP_001034750 P58753  
NM_148910 NP_683708    

Related Sequences

 
mRNAGenPeptSwissProt
BC032474 AAH32474 P58753
AF406652 AAL01160 P58753
AF410783 AAL05036 P58753
AF378129 AAL05627 P58753
AY576785 AAT90417 P58753
AY576786 AAT90418 P58753
AY576787 AAT90419 P58753
DQ890988 ABM81914  
DQ894164 ABM85090  
AK313147 BAG35965 P58753
AK124298 BAG54027 P58753
AB446477 BAG55254 P58753

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TIRAP NP_001034750 M.musculus Tirap 117149 Gene Info NP_001171316 80
R.norvegicus Tirap 680127   XP_001055833 79

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)