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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. RUNX2, runt-related transcription factor 2
Sequence ID:NM_001015051
NM_001024630
NM_004348
RefSeqGene ID:NG_008020
Entrez Gene ID:860
Ensembl ID:ENSG00000124813

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CLEIDOCRANIAL DYSPLASIA 

Cytogenetic Location (from UniGene)

Cytogenetic Location:6p21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 45296059 - 45296520

 Exon Info From UCSC:
NM_001015051
NM_001024630
NM_004348

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100063958Full LengthBC160022runt-related transcription factor 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004339  NP_001015051  NP_001019801  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001015051 NP_001015051   Runt
RunxI
NM_001024630 NP_001019801 Q13950 Runt
RunxI
NM_004348 NP_004339   Runt
RunxI

Related Sequences

 
mRNAGenPeptSwissProt
L40992 AAA89072 Q13950
Q5T801
AF053952 AAC78624 Q13950
BC108919 AAI08920 Q32MY8
BC108920 AAI08921 Q32MY8
BC160022 AAI60022  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens RUNX2 NP_001019801 M.musculus Runx2 12393 Gene Info NP_001139510 99
R.norvegicus Runx2 367218   NP_445922 99
C.elegans rnt-1 172243   NP_491679 38

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)