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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. CLN3, ceroid-lipofuscinosis, neuronal 3
Sequence ID:NM_000086
RefSeqGene ID:NG_008654
Entrez Gene ID:1201
Ensembl ID:ENSG00000188603

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:16p12.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 28488802 - 28503134

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2820893Full LengthBC002394ceroid-lipofuscinosis, neuronal 3
2820893Full LengthBC004433ceroid-lipofuscinosis, neuronal 3
5764535Full LengthBC111068ceroid-lipofuscinosis, neuronal 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000077  

Protein Infomation

NM_000086 NP_000077 Q13286 CLN3
NM_001042432 NP_001035897    

Related Sequences

U32680 AAB51075 Q13286
AF015593 AAD01555 Q13286
AF015594 AAD01556 O95085
AF015595 AAD01557 O95086
AF015596 AAD01558 O95087
AF015597 AAD01559 O95088
AF015598 AAD01560 O95089
AF015599 AAD01561 O95090
AF015600 AAD01562 O95091
AF015601 AAD01563 O95092
AF015602 AAD01564 O95093
AF078168 AAD48542 Q9UP05
AF078169 AAD48543 Q13286
AF077956 AAD51478 Q13286
AF077957 AAD51479 Q13286
AF077958 AAD51480 Q13286
AF077959 AAD51481 Q13286
AF077960 AAD51482 Q13286
AF077961 AAD51483 Q13286
AF077962 AAD51484 Q13286
AF077963 AAD51485 Q13286
AF077964 AAD51486 Q9UBD8
AF077965 AAD51487 Q13286
AF077966 AAD51488 Q13286
AF077967 AAD51489 Q9UP10
AF077968 AAD51490 Q9UBD8
AF077969 AAD51491 Q9UBH5
AF077970 AAD51492 Q9UBH5
AF077971 AAD51493 Q13286
AF077972 AAD51494 Q13286
AF077973 AAD51495 Q9UP08
BC002394 AAH02394 Q13286
BC004433 AAH04433 Q13286
BC111068 AAI11069 Q2TA70
EF587244 ABW04812 A8JYI8
EF587245 ABW04813 A8JYI9
AK313002 BAG35838 Q13286
AK294070 BAG57414 B4DFF3
AK294250 BAG57546 B4DFT5
AK295500 BAG58420 B4DIA8
AK297690 BAG60048 B4DMY6
AK302027 BAG63425 B4DXL3
AK302138 BAG63512 B4DXV0
BK001540 DAA02067 Q5XFT9

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens CLN3 NP_000077 M.musculus Cln3 12752 Gene Info NP_034037 86
R.norvegicus Cln3 293485   NP_001006972 85
A.gambiae AgaP_AGAP003934 1278760   XP_318386 46
C.elegans cln-3.2 172171   NP_491556 46
D.melanogaster cln3 39981   NP_649011 45
C.elegans cln-3.1 179559   NP_505859 44
N.crassa NCU10272 5847217   XP_001728107 44
N.crassa NCU08408 3879435   XP_963280 44
C.elegans cln-3.3 179249   NP_505237 42
S.cerevisiae YHC3 853387   NP_012476 41
S.pombe btn1 2543645   NP_593598 37

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)