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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CRYAB, crystallin, alpha B
Sequence ID:NM_001885
RefSeqGene ID:NG_009824
Entrez Gene ID:1410
Ensembl ID:ENSG00000109846

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stomach, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
CATARACT, POSTERIOR POLAR 2 
MYOPATHY, MYOFIBRILLAR, ALPHA-B CRYSTALLIN-RELATED 
MYOPATHY, MYOFIBRILLAR, FATAL INFANTILE HYPERTROPHY, ALPHA-B CRYSTALLIN-RELATED 

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q22.3-q23.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 111779384 - 111782468

NM_001885 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1342111779349111779690
343465111781050111781172
466691111782247111782472

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3933748Full LengthBC007008crystallin, alpha B

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001876  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001885 NP_001876 P02511 HSP20
Crystallin

Related Sequences

 
mRNAGenPeptSwissProt
M24906 AAA60267 P02511
S45630 AAB23453 P02511
AF007162 AAC19161 P02511
BC007008 AAH07008 P02511
BT006770 AAP35416 P02511
DQ892517 ABM83443  
DQ895729 ABM86655  
FJ876064 ACP18852 C3VMY8
AK314029 BAG36739 P02511
AK295498 BAG58418 B4DIA6
AM392549 CAL37427  
AM393027 CAL37905  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CRYAB NP_001876 M.musculus Cryab 12955 Gene Info NP_034094 98
R.norvegicus Cryab 25420   NP_037067 97
A.gambiae AgaP_AGAP007162 1269952   XP_001688031 50
D.melanogaster l(2)efl 37744   NP_523827 48

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)