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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SMARCB1, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
Sequence ID:NM_001007468
NM_003073
RefSeqGene ID:NG_009303
Entrez Gene ID:6598
Ensembl ID:ENSG00000099956

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
MENTAL RETARDATION, AUTOSOMAL DOMINANT 15 
RHABDOID PREDISPOSITIONSYNDROME 1 

Cytogenetic Location (from UniGene)

Cytogenetic Location:22q11.23|22q11Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:22: 24129356 - 24176367

 Exon Info From UCSC:
NM_001007468
NM_003073

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9052181Full LengthBC143667SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
40125665Full LengthBC117114SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003064  NP_001007469  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001007468 NP_001007469   SNF5
NM_003073 NP_003064 Q12824 SNF5

Related Sequences

 
mRNAGenPeptSwissProt
BC117114 AAI17115 Q12824
BC143667 AAI43668 Q12824
AY207470 AAO59166 Q86WI8
AY207471 AAO59167 Q86WI7
AY207472 AAO59168 Q86WI6
HQ258224 ADR82978  
AK024025 BAB14784 Q9H836
AB017523 BAC77068 Q12824
AK021419 BAG51033 Q12824
AK299411 BAG61393 B4DRT1
AK303620 BAG64629 B4E117
AJ011737 CAA09758 Q12824
AJ011738 CAA09759 Q12824
CR456581 CAG30467 Q12824
CU013180 CAK54611  
CU013468 CAK54910  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SMARCB1 NP_003064 M.musculus Smarcb1 20587 Gene Info NP_035548 100
R.norvegicus Smarcb1 361825   NP_001020899 100
A.gambiae AgaP_AGAP001154 1282012   XP_322006 71
D.melanogaster Snr1 40657   NP_730935 68
C.elegans R07E5.3 175571   NP_497890 55

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta