Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. B2M, beta-2-microglobulin
Sequence ID:NM_004048
RefSeqGene ID:NG_012920
Entrez Gene ID:567
Ensembl ID:ENSG00000166710

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:15q21-q22.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:15: 45003738 - 45010342

NM_004048 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5502428Full LengthBC032589beta-2-microglobulin
6055473Full LengthBC064910beta-2-microglobulin

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004039  

Protein Infomation

NM_004048 NP_004039 P61769 C1-set

Related Sequences

S54761 AAB25312  
S82297 AAD14387 Q16446
S82300 AAD14388 Q9UM88
AF072097 AAD48083 P61769
AY007153 AAG02006 P61769
BC032589 AAH32589 P61769
BC064910 AAH64910 P61769
AY187687 AAO20842 P61769
DQ839493 ABI63354 A6XMH4
DQ839494 ABI63355 A6XMH5
DQ884406 ABI63373 A6XND9
DQ893711 ABM84637  
DQ890551 ABM92168  
AB021288 BAA35182 P61769
AK315776 BAG38125 P61769
AK303560 BAG64583 B4E0X1
V00567 CAA23830 P61769
CR457066 CAG33347 P61769

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens B2M NP_004039 R.norvegicus B2m 24223   NP_036644 70
M.musculus B2m 12010 Gene Info NP_033865 68

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta