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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. KRT8, keratin 8
Sequence ID:NM_001256282
NM_001256293
NM_002273
NR_045962
RefSeqGene ID:NG_008402
Entrez Gene ID:3856
Ensembl ID:ENSG00000170421

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CIRRHOSIS, NONCRYPTOGENICKRT18

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 53290974 - 53298841

Transcript StartTranscript EndChromosomal Start Chromosomal End
74385329097053291401
4394975329224453292302
4987185329246253292682
71910095329355853293848
101011055329437153294466
110611665329494253295002
116713755329564753295855
137618025329844153298867

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2963092Full LengthBC073760keratin 8
3349233Full LengthBC000654keratin 8
3445666Full LengthBC008200keratin 8
3879823Full LengthBC063513keratin 8
6285632Full LengthBC075839keratin 8
3447242IncompleteBC011373keratin 8

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002264  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001256282 NP_001243211    
NM_001256293 NP_001243222    
NM_002273 NP_002264 P05787 Filament

Related Sequences

 
mRNAGenPeptSwissProt
M34225 AAA35748 P05787
M26512 AAA51542 P05787
U76549 AAB18966 P05787
BC000654 AAH00654 P05787
BC008200 AAH08200 Q7L4M3
BC011373 AAH11373 Q969I0
BC063513 AAH63513 P05787
BC073760 AAH73760 P05787
BC075839 AAH75839 P05787
DQ892637 ABM83563  
DQ895875 ABM86801  
AK222941 BAD96661 P05787
AK290938 BAF83627 P05787
AK315826 BAF98717 P05787
X12882 CAA31376 P05787
X74929 CAA52882 P05787
X98614 CAA67203 P05787
AM392826 CAL37704  
AM392892 CAL37770  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens KRT8 NP_002264 M.musculus Krt8 16691 Gene Info NP_112447 92
R.norvegicus Krt8 25626   NP_955402 91
R.norvegicus LOC100362689 100362689   XP_002727937 87

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)