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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. LGI1, leucine-rich, glioma inactivated 1
Sequence ID:NM_005097
RefSeqGene ID:NG_011832
Entrez Gene ID:9211
Ensembl ID:ENSG00000108231

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
EPILEPSY, FAMILIAL TEMPORAL LOBE, 1 
GLIOBLASTOMABRCA2
DMBT1
ERBB2
MSH2
PPARG
PTEN
WDR11

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q24Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 95548081 - 95557915

NM_005097 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
15519551756595518115
5526239551851695518587
6246959553713595537206
6967679553730295537373
7688399554985595549926
84010099555249995552668
101011749555294295553106
117523659555672495557914

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4811956Full LengthBC022500leucine-rich, glioma inactivated 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005088  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_005097 NP_005088 O95970 LRR_1
EPTP

Related Sequences

 
mRNAGenPeptSwissProt
AF055636 AAC99316 O95970
BC022500 AAH22500 O95970
AF473548 AAM22074 O95970
AY358885 AAQ89244 O95970
DQ892371 ABM83297  
DQ895580 ABM86506  
AB209408 BAD92645 Q59FQ2
AK289706 BAF82395 O95970
AK303956 BAG64882 O95970

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens LGI1 NP_005088 M.musculus Lgi1 56839 Gene Info NP_064674 97
R.norvegicus Lgi1 252892   NP_665712 97

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)