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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. EIF2B3, eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
Sequence ID:NM_001166588
NM_001261418
NM_020365
RefSeqGene ID:NG_015864
Entrez Gene ID:8891
Ensembl ID:ENSG00000070785

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
LEUKOENCEPHALOPATHY WITH VANISHING WHITE MATTEREIF2B1
EIF2B2
EIF2B4
EIF2B5

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p34.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 45316513 - 45452256

 Exon Info From UCSC:
NM_001166588
NM_020365

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4849789Full LengthBC018728eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_065098  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001166588 NP_001160060    
NM_001261418 NP_001248347    
NM_020365 NP_065098 Q9NR50 NTP_transferase

Related Sequences

 
mRNAGenPeptSwissProt
AF257077 AAF91351 Q9NR50
BC018728 AAH18728 Q9NR50
AK022399 BAB14027 Q9HA31
AK024006 BAB14770 Q9NR50
AK314668 BAG37225 Q9NR50
AL834288 CAD38962 Q9NR50
CR457285 CAG33566 Q9HA31
AM393609 CAL38485  
AM393782 CAL38657  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens EIF2B3 NP_065098 M.musculus Eif2b3 108067 Gene Info NP_001104747 92
R.norvegicus Eif2b3 171145   NP_598293 90
D.melanogaster eIF2B-gamma 36722   NP_611046 39
S.pombe tif223 2543622   NP_594962 35
A.gambiae AgaP_AGAP005210 1274918   XP_314112 34
C.elegans ppp-1 174138   NP_495428 32
A.thaliana AT5G19485 3770677   NP_001031908 31
N.crassa NCU03548 3871919   XP_955772 27

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta