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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CBS, cystathionine-beta-synthase
Sequence ID:NM_000071
NM_001178008
NM_001178009
RefSeqGene ID:NG_008938
Entrez Gene ID:875
Ensembl ID:ENSG00000160200

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
HOMOCYSTINURIA, B6-RESPONSIVE AND NONRESPONSIVE TYPES 

Cytogenetic Location (from UniGene)

Cytogenetic Location:21q22.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:21: 44473633 - 44496971

 Exon Info From UCSC:
NM_000071
NM_001178008
NM_001178009

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2820694Full LengthBC000440cystathionine-beta-synthase
3028099Full LengthBC007257cystathionine-beta-synthase
3869615Full LengthBC011381cystathionine-beta-synthase
4154798Full LengthBC010242cystathionine-beta-synthase
3608784IncompleteBC012319cystathionine-beta-synthase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000062  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000071 NP_000062 P35520 EC 4.2.1.22 PALP
CBS
NM_001178008 NP_001171479      
NM_001178009 NP_001171480      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L19501 AAA19874 P35520 EC 4.2.1.22
L14577 AAA98524 P35520 EC 4.2.1.22
BC000440 AAH00440 P35520 EC 4.2.1.22
BC007257 AAH07257 P35520 EC 4.2.1.22
BC010242 AAH10242 P35520 EC 4.2.1.22
BC011381 AAH11381 P35520 EC 4.2.1.22
BC012319 AAH12319 Q96EH7  
BT007154 AAP35818 P35520 EC 4.2.1.22
DQ891029 ABM81955    
DQ894208 ABM85134    
AK313691 BAG36440 P35520 EC 4.2.1.22
AK294608 BAH11822 B7Z2D6  
AK301063 BAH13401 B7Z6W5  
X82166 CAA57656 P35520 EC 4.2.1.22
AL137314 CAB70691 Q9NTF0  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CBS NP_000062 M.musculus Cbs 12411 Gene Info NP_835742 85
R.norvegicus Cbs 24250   NP_036654 84
A.gambiae AgaP_AGAP000162 1272101   XP_310977 56
D.melanogaster CG1753 33081   NP_608424 53
N.crassa NCU08216 3875428   XP_959306 53
S.cerevisiae CYS4 853059   NP_011671 50

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)