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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. RNASEH2A, Ribonuclease H2, subunit A
Sequence ID:NM_006397
RefSeqGene ID:NG_012662
Entrez Gene ID:10535
Ensembl ID:ENSG00000104889

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
AICARDI-GOUTIERES SYNDROME 4 

Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 12917397 - 12924280

NM_006397 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
11871291742712917613
1882591291782112917892
2603831291801912918142
3844711291823212918319
4726091292088412921021
6106971292113012921217
6988211292389612924019
82211421292414112924461

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3160621Full LengthBC011748ribonuclease H2, subunit A

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006388  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_006397 NP_006388 O75792 EC 3.1.26.4 RNase_HII

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC011748 AAH11748 O75792 EC 3.1.26.4
AY363912 AAQ64005 Q6UQL6  
AK315327 BAG37728 O75792 EC 3.1.26.4
Z97029 CAB09725 O75792 EC 3.1.26.4
CR456841 CAG33122 Q6IBG3  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens RNASEH2A NP_006388 M.musculus Rnaseh2a 69724 Gene Info NP_081463 87
R.norvegicus Rnaseh2a 364974   NP_001013252 85
A.gambiae AgaP_AGAP007741 1278224   XP_317779 52
C.elegans rnh-2 266861   NP_495796 52
A.thaliana AT2G25100 817048   NP_565584 52
D.melanogaster CG13690 33213   NP_608521 51
S.pombe rnh201 2541542   NP_593684 49
P.falciparum PFF1150w 3885875   XP_966221 48
N.crassa NCU09608 3879521   XP_963372 47
S.cerevisiae RNH201 855652   NP_014327 44

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)