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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. KPNB1, Karyopherin (importin) beta 1
Sequence ID:NM_002265
Entrez Gene ID:3837
Ensembl ID:ENSG00000108424

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q21.32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 45734290 - 45760046

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3162957Full LengthBC036703karyopherin (importin) beta 1
3352610Full LengthBC003572karyopherin (importin) beta 1
3356550Full LengthBC024045karyopherin (importin) beta 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002256  

Protein Infomation

NM_002265 NP_002256 Q14974 Arm

Related Sequences

L38951 AAC41763 Q14974
BC003572 AAH03572 Q14974
BC024045 AAH24045 Q14974
BC036703 AAH36703 Q14974
BT009797 AAP88799 Q14974
DQ892863 ABM83789  
DQ896112 ABM87111  
AK314780 BAG37316 B2RBR9
AK299145 BAH12957 B7Z5M1
AK301463 BAH13488 B7Z752
AK316421 BAH14792 B7ZAV6

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens KPNB1 NP_002256 R.norvegicus Kpnb1 24917   NP_058759 99
M.musculus Kpnb1 16211 Gene Info NP_032405 99
A.gambiae AgaP_AGAP009921 1279333   XP_319040 65
D.melanogaster Fs(2)Ket 35336   NP_477496 62
C.elegans imb-1 172110   NP_491477 49
S.pombe kap95 2542496   NP_594233 42
A.thaliana AT5G53480 835429   NP_200160 41
N.crassa NCU02011 3881025   XP_964876 40
S.cerevisiae KAP95 851061   NP_013451 35

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta