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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. LYST, lysosomal trafficking regulator
Sequence ID:NM_000081
NM_001005736
RefSeqGene ID:NG_007397
Entrez Gene ID:1130
Ensembl ID:ENSG00000143669

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CHEDIAK-HIGASHI SYNDROME 

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q42.1-q42.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 235955069 - 236046974


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4861607IncompleteBC033098lysosomal trafficking regulator
9094484IncompleteBC172908Chediak-Higashi syndrome 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000072  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000081 NP_000072 Q99698 WD40
Beach

Related Sequences

 
mRNAGenPeptSwissProt
U72192 AAB39697 Q99698
U67615 AAB41309 Q99698
U70064 AAB41533 Q99698
L77889 AAB51608 Q99698
U84744 AAB87737 Q99698
BC144702 AAI44703 B7ZMN7

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens LYST NP_000072 R.norvegicus Lyst 85419   NP_445970 86
M.musculus Lyst 17101 Gene Info NP_034878 86

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)