Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. IL6ST, interleukin 6 signal transducer (gp130, oncostatin M receptor)
Sequence ID:NM_001190981
Entrez Gene ID:3572
Ensembl ID:ENSG00000134352

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 55243388 - 55278628

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40125953Full LengthBC117402interleukin 6 signal transducer (gp130, oncostatin M receptor)
40125955Full LengthBC117404interleukin 6 signal transducer (gp130, oncostatin M receptor)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002175  NP_786943  

Protein Infomation

NM_001190981 NP_001177910    
NM_002184 NP_002175 P40189 fn3
NM_175767 NP_786943   fn3

Related Sequences

M57230 AAA59155 P40189
S80479 AAB35921 Q13514
U58146 AAB63010 O15281
BC117402 AAI17403 Q17RA0
BC117404 AAI17405 Q17RA0
HQ258523 ADR83277  
AB015706 BAA78112 P40189
AB102799 BAD89390 Q5FC07
AB102800 BAD89391 Q5FC06
AB102801 BAD89392 Q5FC05
AB102802 BAD89393 P40189
AB102803 BAD89394 Q5FC03
AB102804 BAD89395 Q5FC02

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens IL6ST NP_002175 M.musculus Il6st 16195 Gene Info NP_034690 78
R.norvegicus Il6st 25205   NP_001008725 76

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta