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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PRKCA, protein kinase C, alpha
Sequence ID:NM_002737
RefSeqGene ID:NG_012206
Entrez Gene ID:5578
Ensembl ID:ENSG00000154229

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:17q22-q23.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 64298977 - 64774633

 Exon Info From UCSC:
NM_002737

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40028305Full LengthBC109273protein kinase C, alpha
40028308Full LengthBC109274protein kinase C, alpha
4093756IncompleteBC062759protein kinase C, alpha
6538304IncompleteBC053321protein kinase C, alpha

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002728  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002737 NP_002728 P17252 EC 2.7.11.13 Pkinase
C1_1
C2
Pkinase_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M22199 AAA60098 P17252 EC 2.7.11.13
BC053321 AAH53321 Q7Z727  
BC109273 AAI09274 P17252 EC 2.7.11.13
BC109274 AAI09275 P17252 EC 2.7.11.13
AY633609 AAV33302 Q2TSD3  
EU832768 ACE87779    
GQ129311 ACT64445    
AB209475 BAD92712 Q59FI5  
AB451258 BAG70072 P17252 EC 2.7.11.13
AB451383 BAG70197 P17252 EC 2.7.11.13
X52479 CAA36718 P17252 EC 2.7.11.13

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PRKCA NP_002728 M.musculus Prkca 18750 Gene Info NP_035231 100
R.norvegicus Prkca 24680   NP_001099183 99
D.melanogaster Pkc53E 48311   NP_725626 71
A.gambiae AgaP_AGAP012252 1280437   XP_320290 70

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta