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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PI4KA, phosphatidylinositol 4-kinase, catalytic, alpha
Sequence ID:NM_002650
NM_058004
Entrez Gene ID:5297
Ensembl ID:ENSG00000241973

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pineal gland, pituitary gland, placenta, pooled tissue, prostate, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:22q11.21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:22: 21061989 - 21213070

 Exon Info From UCSC:
NM_002650
NM_058004

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100069092Full LengthBC172398phosphatidylinositol 4-kinase, catalytic, alpha
3912560IncompleteBC018120phosphatidylinositol 4-kinase, catalytic, alpha
5757080IncompleteBC053654phosphatidylinositol 4-kinase, catalytic, alpha
6154581IncompleteBC046202phosphatidylinositol 4-kinase, catalytic, alpha polypeptide

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002641  NP_477352  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002650 NP_002641     PI3_PI4_kinase
PI3Ka
NM_058004 NP_477352 P42356 EC 2.7.1.67 PI3_PI4_kinase
PI3Ka

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L36151 AAA56839 P42356 EC 2.7.1.67
AF012872 AAD13352 P42356 EC 2.7.1.67
BC018120 AAH18120 P42356 EC 2.7.1.67
BC053654 AAH53654 P42356 EC 2.7.1.67
BC172398 AAI72398 P42356 EC 2.7.1.67
AB210002 BAE06084 Q4LE69  
AK314781 BAG37317 B2RBS0  
AK095811 BAG53136 B3KTM4  
AK302424 BAG63727 B4DYG5  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PI4KA NP_477352 M.musculus Pi4ka 224020 Gene Info NP_001001983 98
R.norvegicus Pi4ka 64161   NP_071637 97
A.gambiae AgaP_AGAP010801 4577816   XP_318507 50
D.melanogaster CG10260 31247   NP_570014 49
C.elegans Y75B8A.24 176653   NP_499596 42
A.thaliana ATPI4K ALPHA 841357   NP_850960 31

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)