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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. BACE2, Beta-site APP-cleaving enzyme 2
Sequence ID:NM_012105
NM_138991
NM_138992
Entrez Gene ID:25825
Ensembl ID:ENSG00000182240

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:21q22.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:21: 42540083 - 42647749

 Exon Info From UCSC:
NM_012105
NM_138991
NM_138992

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4868925Full LengthBC014453beta-site APP-cleaving enzyme 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_620476  NP_620477  NP_036237  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_012105 NP_036237 Q9Y5Z0 EC 3.4.23.45 Asp
NM_138991 NP_620476     Asp
NM_138992 NP_620477     Asp

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF117892 AAD45240 Q9Y5Z0 EC 3.4.23.45
AF050171 AAD45963 Q9Y5Z0 EC 3.4.23.45
AF200192 AAF13714 Q9Y5Z0 EC 3.4.23.45
AF200342 AAF17078 Q9Y5Z0 EC 3.4.23.45
AF204944 AAF26368 Q9Y5Z0 EC 3.4.23.45
AF178532 AAF29494 Q9Y5Z0 EC 3.4.23.45
AF188276 AAF35835 Q9Y5Z0 EC 3.4.23.45
AF188277 AAF35836 Q9Y5Z0 EC 3.4.23.45
AF212252 AAG41783 Q9Y5Z0 EC 3.4.23.45
BC014453 AAH14453 Q9Y5Z0 EC 3.4.23.45
AY358927 AAQ89286 Q9Y5Z0 EC 3.4.23.45
DQ895416 ABM86342    
EU176330 ABW03781    
AK075539 BAC11682 Q9Y5Z0 EC 3.4.23.45
AK292056 BAF84745 Q9Y5Z0 EC 3.4.23.45

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens BACE2 NP_036237 R.norvegicus Bace2 288227   NP_001002802 90
M.musculus Bace2 56175 Gene Info NP_062390 89

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)