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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. FTO, fat mass and obesity associated
Sequence ID:NM_001080432
RefSeqGene ID:NG_012969
Entrez Gene ID:79068
Ensembl ID:ENSG00000140718

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
OBESITYADRB2
ADRB3
AGRP
CARTPT
ENPP1
GHRL
MC3R
MC4R
NR0B2
POMC
PPARG
PPARGC1B
PYY
SDC3
SIM1
UCP1
UCP2
UCP3
UCP3

Cytogenetic Location (from UniGene)

Cytogenetic Location:16q12.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 53738090 - 54148365

NM_001080432 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
12675373787453738140
2683455384405153844128
3469735385977553860402
97411175387806653878209
111811975390769753907776
119813415391375553913898
134214615392274353922862
146215865396789653968020
158742915414567354148377

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100016381Full LengthBC153032fat mass and obesity associated
3453653IncompleteBC001284FTO protein
100015377BC148442fat mass and obesity associated

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001080432 NP_001073901 Q9C0B1  

Related Sequences

 
mRNAGenPeptSwissProt
U79260 AAB50206 Q99770
BC003583 AAH03583 Q9C0B1
BC030798 AAH30798 Q9C0B1
BC132892 AAI32893 Q9C0B1
BC137091 AAI37092 Q9C0B1
BC148442 AAI48443  
BC153032 AAI53033  
AB051539 BAB21843 Q9C0B1
AK096554 BAG53322 B3KU60
AK295196 BAG58196 B4DHN4

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FTO NP_001073901 R.norvegicus Fto 291905   NP_001034802 88
M.musculus Fto 26383 Gene Info NP_036066 87

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)