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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. SORBS3, Sorbin and SH3 domain containing 3
Sequence ID:NM_005775
RefSeqGene ID:NG_030586
Entrez Gene ID:10174
Ensembl ID:ENSG00000120896

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:8p21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 22409461 - 22433007

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6186182Full LengthBC067260sorbin and SH3 domain containing 3
6201273Full LengthBC091514sorbin and SH3 domain containing 3
3628014IncompleteBC004314sorbin and SH3 domain containing 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001018003  NP_005766  

Protein Infomation

NM_001018003 NP_001018003   SH3_1
NM_005775 NP_005766 O60504 SH3_1

Related Sequences

AF037261 AAC09244 O60504
AF064807 AAD32304 O60504
BC004314 AAH04314 Q9BT70
BC010146 AAH10146 O60504
BC067260 AAH67260 O60504
BC091514 AAH91514 O60504
AK301196 BAG62776 B4DVR4
AK303950 BAG64877 B4E1R5

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SORBS3 NP_005766 M.musculus Sorbs3 20410 Gene Info NP_035496 83
R.norvegicus Sorbs3 282843   NP_001005762 83

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)