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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. NDUFS4, NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
Sequence ID:NM_002495
RefSeqGene ID:NG_008200
Entrez Gene ID:4724
Ensembl ID:ENSG00000164258

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
LEIGH SYNDROMEBCS1L
COX15
DLD
FOXRED1
NDUFA10
NDUFA12
NDUFA2
NDUFA9
NDUFAF2
NDUFAF6
NDUFS3
NDUFS7
NDUFS8
NDUFV1
SDHA
SURF1
MITOCHONDRIAL COMPLEX I DEFICIENCYFOXRED1
NDUFA1
NDUFA11
NDUFAF1
NDUFAF2
NDUFAF3
NDUFAF4
NDUFAF5
NDUFB3
NDUFS1
NDUFS1
NDUFS2
NDUFS6
NDUFV1
NDUFV2
NUBPL

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q11.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 52965910 - 52968053

NM_002495 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
11265285646452856589
1272055289928152899359
2063785294206252942234
3794525295438052954453
4536765297894752979170

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3681312Full LengthBC005270NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002486  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_002495 NP_002486 O43181 ETC_C1_NDUFA4

Related Sequences

 
mRNAGenPeptSwissProt
AF020351 AAB87865 O43181
BC005270 AAH05270 O43181
HQ448017 ADQ32498  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NDUFS4 NP_002486 M.musculus Ndufs4 17993 Gene Info NP_035017 88
R.norvegicus Ndufs4 499529   NP_001020317 88
A.gambiae AgaP_AGAP007082 1270020   XP_308676 59
D.melanogaster CG12203 32936   NP_573385 56
C.elegans lpd-5 172037   NP_491359 50
A.thaliana FRO1 836895   NP_201560 41

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)