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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SPHK2, sphingosine kinase 2
Sequence ID:NM_001204158
NM_001204159
NM_001204160
NM_001243876
NM_020126
RefSeqGene ID:NG_029867
Entrez Gene ID:56848
Ensembl ID:ENSG00000063176

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:19q13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 49129214 - 49133547

Transcript StartTranscript EndChromosomal Start Chromosomal End
12534912254749122799
2544054912365849123809
4068774912914749129618
87810274913094849131097
102811224913123149131325
112312384913141849131533
123929624913193749133660

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3677636Full LengthBC006161sphingosine kinase 2
3870258Full LengthBC010671sphingosine kinase 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_064511  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001204158 NP_001191087      
NM_001204159 NP_001191088      
NM_001204160 NP_001191089      
NM_001243876 NP_001230805      
NM_001352 NP_001343 Q10586   bZIP_2
NM_020126 NP_064511 Q9NRA0 EC 2.7.1.91 DAGK_cat

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U06936 AAA81374 Q10586  
U79283 AAB50219 Q10586  
AF245447 AAF74124 Q9NRA0 EC 2.7.1.91
BC006161 AAH06161 Q9NRA0 EC 2.7.1.91
BC010671 AAH10671 Q9NRA0 EC 2.7.1.91
BC011965 AAH11965 Q10586  
BT006836 AAP35482 Q10586  
EF107108 ABK81123 A0T4C8  
DQ896790 ABM87789    
EU176470 ABW03921    
D28468 BAA05833 Q10586  
AK000599 BAA91280 Q9NRA0 EC 2.7.1.91
AK074601 BAC11085 Q8N2M3  
AB100373 BAC55583 Q86YZ5  
AB208807 BAD92044 Q59HF2  
AK122735 BAG53695 B3KV83  
AK300541 BAG62249 B4DU87  
AK297787 BAH12667 B7Z4T1  
AL136701 CAB66636 Q9NRA0 EC 2.7.1.91

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SPHK2 NP_001191088 R.norvegicus Sphk2 308589   NP_001012066 85
M.musculus Sphk2 56632 Gene Info NP_975009 84
D.melanogaster Sk2 326219   NP_647762 38
A.gambiae AgaP_AGAP006995 1270104   XP_308775 36

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)