Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SOCS3, suppressor of cytokine signaling 3
Sequence ID:NM_003955
RefSeqGene ID:NG_016851
Entrez Gene ID:9021
Ensembl ID:ENSG00000184557

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:17q25.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 76354432 - 76355282

NM_003955 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1324187635285876355263
241927467635583076356157

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
30333577Full LengthBC060858suppressor of cytokine signaling 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003946  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_003955 NP_003946 Q6FI39
O14543
SH2
SOCS_box

Related Sequences

 
mRNAGenPeptSwissProt
AF159854 AAD42231 Q6FI39
O14543
BC060858 AAH60858 Q6FI39
O14543
BT019544 AAV38351 Q5U0H7
AB004904 BAA22430 O14543
AB006967 BAA22537 Q6FI39
O14543
AK314212 BAG36886 Q6FI39
CR536497 CAG38736 Q6FI39
O14543
CR541694 CAG46495 Q6FI39
O14543
AM392896 CAL37774  
AM393146 CAL38024  
AM393491 CAL38368  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SOCS3 NP_003946 M.musculus Socs3 12702 Gene Info NP_031733 97
R.norvegicus Socs3 89829   NP_446017 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta