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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. ENPP1, ectonucleotide pyrophosphatase/phosphodiesterase 1
Sequence ID:NM_006208
RefSeqGene ID:NG_008206
Entrez Gene ID:5167
Ensembl ID:ENSG00000197594

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ARTERIAL CALCIFICATION, GENERALIZED,OF INFANCY, 1 
DIABETES MELLITUS, NON-INSULIN-DEPENDENTABCC8
AKT2
CDKAL1
GCGR
GCK
GPD2
HMGA1
HMGA1
HNF1A
HNF1B
HNF4A
IGF2BP2
IL6
IRS1
IRS2
KCNJ11
LIPC
MAPK8IP1
MTNR1B
NEUROD1
NEUROD1
NEUROD1
PAX4
PDX1
PPARG
PTPN1
RETN
SLC2A4
SLC30A8
TCF7L2
VEGFA
WFS1
WFS1
HYPOPHOSPHATEMIC RICKETS, AUTOSOMAL RECESSIVE, 2 
OBESITYADRB2
ADRB3
AGRP
CARTPT
FTO
GHRL
MC3R
MC4R
NR0B2
POMC
PPARG
PPARGC1B
PYY
SDC3
SIM1
UCP1
UCP2
UCP3
UCP3
OSSIFICATION OF POSTERIOR LONGITUDINAL LIGAMENT OF SPINECOL6A1

Cytogenetic Location (from UniGene)

Cytogenetic Location:6q22-q23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 132129328 - 132211651

 Exon Info From UCSC:
NM_006208

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
30341060Full LengthBC059375ectonucleotide pyrophosphatase/phosphodiesterase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006199  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_006208 NP_006199 P22413 EC 3.6.1.9
EC 3.1.4.1
Somatomedin_B
Phosphodiest

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M57736 AAA63237 P22413 EC 3.6.1.9
EC 3.1.4.1
BC059375 AAH59375 P22413 EC 3.6.1.9
EC 3.1.4.1
D12485 BAA02054 P22413 EC 3.6.1.9
EC 3.1.4.1
AK314870 BAG37385 B2RBY8  
BX537580 CAD97789 Q7Z3P5  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ENPP1 NP_006199 M.musculus Enpp1 18605 Gene Info NP_032839 81
R.norvegicus Enpp1 85496   NP_445987 80
A.thaliana AT4G29680 829089   NP_194697 42
C.elegans C27A7.1 179663   NP_001041085 32
C.elegans C27A7.3 179665   NP_001041087 31

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta